Case Study

Ischemic Mitral Regurgitation

A 51 year old female patient presented to the ER with gradually worsening shortness of breath.

She had a history of coronary artery disease and ischemic mitral regurgitation treated with CABG and mitral valve repair three years earlier. On clinical examination a holosystolic apical murmur was noted. Her jugular veins were dilated and lower limb edema was present. Bedside examination with KOSMOS revealed impaired systolic function of both ventricles accompanied by severe residual ischemic mitral regurgitation and significant functional tricuspid regurgitation. Intravenous diuresis was promptly initiated resulting in improvement of her symptoms.

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Video 1

PLAX view showing dilated left ventricle with segmental wall motion abnormalities and impaired systolic function. A prosthetic mitral annuloplasty ring is seen and there is restriction of the posterior mitral valve leaflet. A left pleural effusion is also visible.

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Video 2

PLAX view with color showing severe residual mitral regurgitation

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Video 3

RV inflow view

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Video 4

RV inflow view with color showing significant tricuspid regurgitation

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Video 5

CW TR signal from RV inflow view

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Video 6

PSAX view at the level of the papillary muscles demonstrating severely impaired LV systolic function and the presence of segmental wall motion abnormalities

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Video 7

A4C view showing dilated LV with segmental wall motion abnormalities and impaired LV systolic function. The RV is hyperdynamic with overall mildly impaired RV systolic function. There is lack of coaptation of the TV leaflets. Bi-atrial enlargement is also evident.

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Video 8

A4C view with color on the TV showing severe TR

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Video 9

CW TR signal from the A4C view

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Video 10

Assessment of TAPSE with the use of M-mode from the A4C view

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Video 11

A4C view with color on the repaired mitral valve showing severe residual MR

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Video 12

CW MR signal from the A4C view

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Video 13

Subcostal view showing dilated IVC with minimal respiratory variation

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Video 14

PW Doppler in the hepatic veins demonstrating systolic flow reversal suggestive of severe TR

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